Retinoid X Receptor gamma anticorps

N° du produit ABIN7863359

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoid X Receptor gamma dans ELISA, IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Retinoid X Receptor gamma anticorps (ABIN7863359)

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor gamma est non-conjugé

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-RXRG-5H4

Détail du produit anti-Retinoid X Receptor gamma anticorps

Fonction: RXRG / NR2B3 (Transcription Factor) Antibody

Specificité: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR°™, RXR æ and RXRÁ, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human RXRG protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Retinoid X Receptor gamma

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Autre désignation: RXRG

Sujet:

Nuclear receptor subfamily 2 group B member 3 (NR2B3), Retinoic X receptor gamma (RXRG), Retinoic acid receptor RXR gamma, RXR gamma, RXRC

SK-MEL-30, U-2 OS or HeLa cells.

Poids moléculaire: 50.87kDa

ID gène: 6258, 26550

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway