SNW1 anticorps

N° du produit ABIN7864443

Cet anticorps Souris Monoclonal détecte spécifiquement SNW1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SNW1 anticorps (ABIN7864443)

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNW1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: PCRP-SNW1-1C12

Détail du produit anti-SNW1 anticorps

Fonction: SNW1 Antibody

Specificité: Nuclear receptor coactivator NCOA62/SNW1 (Nuclear Protein SkiP, SKIIP ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment of human SNW1 protein

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur SNW1

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Autre désignation: SNW1

Sujet:

Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP

HeLa or U87 cells. General nuclear expression.

Poids moléculaire: 61.49kDa

ID gène: 22938, 25040

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway