Recombinant Thrombomodulin anticorps
Aperçu rapide pour Recombinant Thrombomodulin anticorps (ABIN7864303)
Antigène
Voir toutes Thrombomodulin (THBD) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Recombinant Thrombomodulin / CD141 (Endothelial Cell Marker) Antibody
-
Specificité
- It recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
-
Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
Immunogène
- Recombinant full-length human Thrombomodulin (CD141) protein
-
Isotype
- IgG, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 200 μg/mL
-
Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- Thrombomodulin (THBD)
-
Autre désignation
- Thrombomodulin
-
Sujet
-
AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM)
Angiosarcoma|Bladder or Cervical Carcinoma.|Placenta, Lung
-
Poids moléculaire
- ~100kDa
-
ID gène
- 7056, 2030
-
UniProt
- P07204
Antigène
-