TSHB anticorps

N° du produit ABIN7862172

L’anticorps anti-TSHB Monoclonal Souris est utilisé pour la détection de TSHB dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour TSHB anticorps (ABIN7862172)

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSHB est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: TSHb-1317

Détail du produit anti-TSHB anticorps

Fonction: Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) Antibody

Specificité: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human TSH beta fragment

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10  mM PBS with 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TSHB

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Autre désignation: Thyroid Stimulating Hormone, beta

Sujet:

CHNG4, Thyroid stimulating hormone beta subunit, Thyroid stimulating hormone, beta precursor, Thyrotropin beta subunit, TSHB

Normal pituitary or pituitary tumor.

Poids moléculaire: 16kDa

ID gène: 7252, 406687

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism