TGFB2 anticorps
Aperçu rapide pour TGFB2 anticorps (ABIN7862202)
Antigène
Voir toutes TGFB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- TGFB2 (Transforming Growth Factor beta 2) Antibody
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Specificité
- Transforming growth factor bs (TGFbs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFa. It is now realized that TGFbs mediate many cell-cell interactions that occur during embryonic development. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80 % identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human TGFB2 protein
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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Autre désignation
- TGFB2
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Sujet
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Transforming Growth Factor beta 2, TGF b2
Prostate or lung carcinoma.
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Poids moléculaire
- 13kDa
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ID gène
- 7042, 645227
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UniProt
- P10600
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Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Antigène
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