ZNF202 anticorps
Aperçu rapide pour ZNF202 anticorps (ABIN7864550)
Antigène
Voir toutes ZNF202 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- ZNF202 Antibody
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Specificité
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF202 (zinc finger protein 202), also known as ZKSCAN10, is a 648 amino acid protein that contains eight C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. Localized to the nucleus and expressed at high levels in the testis, ZNF202 belongs to the Kruppel C2H2-type zincfinger protein family and functions as a transcriptional repressor of genes that are involved in lipid metabolism. ZNF202 regulates the expression of several classes of proteins, including lipoprotein particles, transporters involved in lipid homeostasis, enzymes involved in lipid processing and a wide variety of proteins that are associated with energy metabolism. Defects in the gene encoding ZNF202 are associated with high cholesterol and may be involved in the pathogenesis of lung, ovarian and breast cancer. Two isoforms of ZNF202, designated a and b, exist due to alternative splicing events
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around 37-132) of human ZNF202 protein
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- ZNF202 (Zinc Finger Protein 202 (ZNF202))
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Autre désignation
- ZNF202
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Sujet
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ZKSCAN10, ZSCAN42
HeLa or MCF-7 cells.
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Poids moléculaire
- 74.72kDa
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ID gène
- 7753, 112556
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UniProt
- O95125
Antigène
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