ZNF276 anticorps
Aperçu rapide pour ZNF276 anticorps (ABIN7863602)
Antigène
Voir toutes ZNF276 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- ZNF276 (Transcription Factor) Antibody
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Specificité
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human ZNF276 protein
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- ZNF276 (Zinc Finger Protein 276 (ZNF276))
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Autre désignation
- ZNF276
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Sujet
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AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477
HeLa or K562 cells.
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Poids moléculaire
- ~67kDa
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ID gène
- 92822, 290154
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UniProt
- Q8N554
Antigène
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