Recombinant LI Cadherin anticorps (AA 242-418)

N° du produit ABIN7862372

Cet anticorps Souris Monoclonal détecte spécifiquement LI Cadherin dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant LI Cadherin anticorps (AA 242-418) (ABIN7862372)

Antigène: LI Cadherin

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LI Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RCDH17-8514

Détail du produit anti-LI Cadherin anticorps

Épitope: AA 242-418

Fonction: Recombinant Cadherin 17 / LI Cadherin (Gastric Adenocarcinoma Marker) Antibody

Specificité: It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

Purification: 200ug/ml of Ab purified from rabbit anti-serum by Protein A.

Immunogène: Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur LI Cadherin

Antigène: LI Cadherin

Autre désignation: Cadherin 17

Sujet:

BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin

Human stomach, colon, liver or small intestine. HepG2 or HT29 cells.

Poids moléculaire: 92kDa

ID gène: 1015, 591853

UniProt: Q12864