Recombinant LI Cadherin anticorps (AA 242-418)

N° du produit ABIN7862374

Cet anticorps anti-LI Cadherin Monoclonal Lapin (Clone CDH17-8515R) (ABIN7862374) détecte spécifiquement LI Cadherin dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant LI Cadherin anticorps (AA 242-418) (ABIN7862374)

Antigène: LI Cadherin

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LI Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CDH17-8515R

Détail du produit anti-LI Cadherin anticorps

Épitope: AA 242-418

Fonction: Recombinant Cadherin 17 / LI Cadherin (Gastric Adenocarcinoma Marker) Antibody

Specificité: It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

Purification: 200ug/ml of Ab purified from rabbit anti-serum by Protein A.

Immunogène: Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur LI Cadherin

Antigène: LI Cadherin

Autre désignation: Cadherin 17

Sujet:

BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin

Human stomach, colon, liver or small intestine.

Poids moléculaire: 120kDa

ID gène: 1015, 591853

UniProt: Q12864