MUC1 anticorps

N° du produit ABIN7863167

Cet anticorps Souris Monoclonal détecte spécifiquement MUC1 dans IHC, WB, FACS et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MUC1 anticorps (ABIN7863167)

Antigène: MUC1 (Mucin 1 (MUC1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: Mc5

Détail du produit anti-MUC1 anticorps

Fonction: MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody

Specificité: The mucin antigen recognized by Mc-5 is a glycosylated molecule with a molecular mass of 400 kD. The sequence to which this antibody binds is Thr-Arg-Pro-Ala-Pro. Although EMA is primarily located in mammary gland epithelium, other normal epithelia (e.g., lung) will also react against EMA antibody. Staining, however, is the strongest in mammary epithelia. The combination of positive staining for keratin with negative EMA can be used to phenotype the above-mentioned epithelial tumors. Recognizes the mucin antigen that is present in most epithelial tissues (breast, colonic, bronchial, gastric, etc.) This antibody does not recognize myelopoietic, lymphopoietic, fibroblasts or sarcomatous cells.

Purification: 200ug/ml of recombinant MAb purified by Protein A/G.

Immunogène: Delipidated human milk fat globules

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC1

Sujet:

Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen

Human kidney, lung, breast carcinoma or normal breast.

Poids moléculaire: 400kDa

ID gène: 4582, 89603

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling