Recombinant CEA anticorps
Aperçu rapide pour Recombinant CEA anticorps (ABIN7865504)
Antigène
Voir toutes CEA AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Expression System
- HEK-293 Cells
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Fonction
- Recombinant Carcinoembryonic Antigen (CEA) / CD66 Antibody
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Specificité
- This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
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Purification
- Ab produced in HEK293 cell mammalian-based expression system.
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Immunogène
- Recombinant full-length human CEA protein
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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Autre désignation
- Carcinoembryonic Antigen
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Sujet
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Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)
Colon: An at least moderate cytoplasmic CEA staining should be seen in the vast majority of columnar epithelial cells.
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Poids moléculaire
- 80-200kDa
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ID gène
- 1048, 709196
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UniProt
- P06731
Antigène
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