Recombinant MLANA anticorps

N° du produit ABIN7865521

L’anticorps anti-MLANA Monoclonal Souris est utilisé pour la détection de MLANA dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant MLANA anticorps (ABIN7865521)

Antigène: MLANA (Melan A (MLANA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MLANA est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MSVA-900M

Détail du produit anti-MLANA anticorps

Expression System: HEK-293 Cells

Fonction: Recombinant MART-1 / Melan-A / MLANA (Melanoma Marker) Antibody

Specificité: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Purification: Ab produced in HEK293 cell mammalian-based expression system.

Immunogène: Recombinant full-length hMART-1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MLANA

Antigène: MLANA (Melan A (MLANA))

Autre désignation: MART-1

Sujet:

Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA

Skin: Virtually all melanocytes should show a strong Melan A- immunostaining including a weak to moderate staining in melanocytic dendrites.

Poids moléculaire: 20-22kDa (doublet)

ID gène: 2315, 154069

UniProt: Q16655