Cet anticorps anti-AMACR Monoclonal Souris (Clone IHC504) (ABIN7865557) détecte spécifiquement AMACR dans IHC.
L’anticorps est réactif avec des échantillons de Humain.
Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
store at 2 - 8 °C
Antigène
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
Autre désignation
p504s
Sujet
P504s, also known as α-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in β-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.