CD46 anticorps

N° du produit ABIN7865595

L’anticorps anti-CD46 Monoclonal Souris est utilisé pour la détection de CD46 dans des échantillons de Humain. Il a été validé pour FACS, IHC, IF et ICC.

Aperçu rapide pour CD46 anticorps (ABIN7865595)

Antigène: CD46

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 197-2B1

Détail du produit anti-CD46 anticorps

Fonction: anti-CD46 mouse monoclonal, 197-2B1, purified

Purification: affinity chromatography

Immunogène: stimulated human leucocytes

Isotype: IgG2a kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: 197-2B1 reacts with human CD46, a 52-58 kDa single chain type 1 transmembrane molecule. CD46 is a cofactor for the factor I regulation of complement components C3b and C4b and contains four N-terminal short consensus repeat (SCR) modules. It is strongly expressed on salivary gland ducts and kidney ducts and often increased on tumor cells. It is also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. 197-2B1 has been clustered at the VIth HLDA Workshop. Positive control: K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.

Pathways: Regulation of Actin Filament Polymerization