CDw17 anticorps

N° du produit ABIN7865612

Cet anticorps Souris Monoclonal détecte spécifiquement CDw17 dans FACS, IF, ICC et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDw17 anticorps (ABIN7865612)

Antigène: CDw17

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Clone: EBS-CD-014

Détail du produit

Fonction: anti-CDw17 mouse monoclonal, EBS-CD-014, purified

Purification: affinity chromatography

Immunogène: beta-2 microglobulin associated proteins from a detergent lysate of human PBL

Isotype: IgM kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détail du antigène

Antigène: CDw17

Sujet: CDw17 is an intermediate glycosphingolipid from the metabolism of higher gangliosides that localizes to sphingolipid-sterol rafts. CDw17 is found on monocytes, granulocytes, basophils, platelets, a subset of peripheral B-cells (CD19+) and tonsil dendritic cells. It is rapidly down regulated on activated granulocytes and is upregulated on IL-2 activated T-lymphocytes. CDw17 binds to bacteria and may function in phagocytosis. It may also be involved in angiogenesis. Aberrant levels of glycosphingolipids are a feature of cancer cells and may influence integrin clustering and internalization. Positive control: Human PBL and tonsil.