hCG Holo anticorps

N° du produit ABIN7865643

L’anticorps anti-hCG Holo Monoclonal Souris est utilisé pour la détection de hCG Holo dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour hCG Holo anticorps (ABIN7865643)

Antigène: hCG Holo

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Clone: HCGh25

Détail du produit

Fonction: anti-hCG Holo mouse monoclonal, HCGh25, purified

Purification: affinity chromatography

Immunogène: purified hCG

Isotype: IgG1 kappa

Information d'application

Indications d'application:

IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détail du antigène

Antigène: hCG Holo

Sujet: HCGh25 is very special because it reacts ONLY with intact-hCG and not with either free alpha- or free beta-chain of hCG. hCG is a glycoprotein composed of two non-identical, non-covalently linked polypeptide chains. The alpha subunit is identical among hCG, TSH, FSH and LH. While hCG is secreted in large quantities by normal trophoblasts, it is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. Besides trophoblastic tumors e.g. choriocarcinoma, large cell carcinoma, adenocarcinoma and squamous cell carcinoma of the lung are also positive in 90 % , 60 % and 20 % of cases respectively. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Positive control: JAR or TT Cells. Placenta.