kappa Light Chain anticorps

N° du produit ABIN7865676

L’anticorps anti-kappa Light Chain Monoclonal Souris est utilisé pour la détection de kappa Light Chain dans des échantillons de Humain. Il a été validé pour FACS, IHC, IF, ICC et ELISA.

Aperçu rapide pour kappa Light Chain anticorps (ABIN7865676)

Antigène: kappa Light Chain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp kappa Light Chain est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA

Clone: EBS-huKappa

Détail du produit anti-kappa Light Chain anticorps

Fonction: anti-Kappa-Light-Chain mouse monoclonal, EBS-huKappa, purified

Réactivité croisée (Details): negative with rat

Purification: affinity chromatography

Immunogène: B lymphoma cells

Isotype: IgG1 kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:100 - 1:200 (0.5 - 1.0 μg/mL)

FACS_dilution: 0.5 - 1.0 μg/million cells in 0.1 ml

IHC-paraffin_dilution: 1:50 - 1:100 (1 - 2 μg/mL, microwave treatment recommended)

IHC-frozen_dilution: 1:50 - 1:100 (1 - 2 μg/mL)

elisa_dilution: 1:1 - 1:100,000 (0.001 - 100 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0,02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur kappa Light Chain

Antigène: kappa Light Chain

Autre désignation: Kappa-Light-Chain

Sujet: EBS-huKappa reacts with kappa light chain In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicate tha the infiltrate is malignant. Positive control: 293T, Raji or hPBL cells, tonsil or spleen.