PAX5 anticorps

N° du produit ABIN7865710

Cet anticorps anti-PAX5 Monoclonal Souris (Clone IHC005) (ABIN7865710) détecte spécifiquement PAX5 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PAX5 anticorps (ABIN7865710)

Antigène: PAX5 (Paired Box 5 (PAX5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX5 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: IHC005

Détail du produit anti-PAX5 anticorps

Fonction: anti-PAX-5 mouse monoclonal, IHC005, purified

Purification: affinity chromatography

Immunogène: Recombinant Human PAX-5

Isotype: IgG1

Information d'application

Indications d'application: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur PAX5

Antigène: PAX5 (Paired Box 5 (PAX5))

Autre désignation: PAX-5

Sujet: PAX5 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP), whose expression is limited to early stages of B-cell differentiation. Anti-PAX5 is useful in differentiating between classic Hodgkin's lymphoma versus multiple myeloma and solitary plasmacytoma, as the protein is expressed in mature and precursor B-cell non-Hodgkin's lymphomas/leukemias while being absent from the other two conditions. Diffuse large B-cell lymphomas are positive for PAX5, with the exception of those with terminal B-cell differentiation, and T-cell neoplasms do not stain with Anti-PAX5.