SALL4 anticorps

N° du produit ABIN7865730

L’anticorps anti-SALL4 Monoclonal Souris est utilisé pour la détection de SALL4 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour SALL4 anticorps (ABIN7865730)

Antigène: SALL4 (Sal-Like 4 (SALL4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SALL4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: IHC659

Détail du produit anti-SALL4 anticorps

Fonction: anti-SALL4 mouse monoclonal, IHC659, purified

Purification: affinity chromatography

Immunogène: Recombinant Human SALL4

Isotype: IgG1

Information d'application

Indications d'application: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur SALL4

Antigène: SALL4 (Sal-Like 4 (SALL4))

Autre désignation: SALL4

Sujet: Sal-Like Protein 4 (SALL4) is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumours (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germcell tumours, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.

Pathways: Stem Cell Maintenance, Tube Formation