CD56 anticorps
Aperçu rapide pour CD56 anticorps (ABIN7866124)
Antigène
Voir toutes CD56 (NCAM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Mouse anti Human CD56 Prediluted
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Attributs du produit
- NCAM / CD56, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM can be found in central and peripheral nerve cells, neuroendocrine tissues and at the surface of NK-cells. Also, NCAM is present in malignancies derived from these tissues and cells.
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Purification
- Protein A/G Chromatography
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Immunogène
- Extract from KG1a cell line.,Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c F1 mice immunized with KG1a cell line.
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Isotype
- IgG2b
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Indications d'application
- Product provided in dropper bottle and should be used as provided. Use 2-3 drops per section or sufficient solution to cover section.
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Restrictions
- For Research Use only
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Buffer
- Prediluted monoclonal antibody C5.9 in PBS containing 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Product should be stored at 4-8°C. DO NOT FREEZE
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Autre désignation
- CD56
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Sujet
- CD56, NCAM, Neural Cell Adhesion Molecule
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UniProt
- P13591
Antigène
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