CD46 anticorps (PE)

N° du produit ABIN7867164

L’anticorps anti-CD46 Monoclonal Lapin est utilisé pour la détection de CD46 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour CD46 anticorps (PE) (ABIN7867164)

Antigène: CD46

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DM145

Détail du produit anti-CD46 anticorps (PE)

Fonction: PE-conjugated Anti-CD46 antibody(DM145), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet:

Synonyms: CD46,AHUS2,MCP,MIC10,TLX,TRA2.10

Target Background: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization