Recombinant SELPLG anticorps (PE)
Aperçu rapide pour Recombinant SELPLG anticorps (PE) (ABIN7867426)
Antigène
Voir toutes SELPLG AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- PE-conjugated Anti-CD162 antibody(DMC283), IgG1 Chimeric mAb
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Isotype
- IgG1
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Indications d'application
- Flow Cyt 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2°C-8°C for 6 months
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Date de péremption
- 6 months
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- SELPLG (Selectin P Ligand (SELPLG))
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Autre désignation
- SELPLG
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Sujet
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Synonyms: PSGL-1,PSGL1,CD162,SELPLG,Selectin P ligand
Target Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
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UniProt
- Q14242
Antigène
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