Recombinant SIGLEC7 anticorps (PE)

N° du produit ABIN7867430

Cet anticorps Lapin Chimeric détecte spécifiquement SIGLEC7 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant SIGLEC7 anticorps (PE) (ABIN7867430)

Antigène: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp SIGLEC7 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DMC475

Détail du produit anti-SIGLEC7 anticorps (PE)

Fonction: PE-conjugated Anti-SIGLEC7 antibody(DMC475), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur SIGLEC7

Antigène: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Autre désignation: SIGLEC7

Sujet:

Synonyms: AIRM-1, AIRM1, CD328, CDw328, D-siglec, p75, p75:AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2

Target Background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34 cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).[UniProtKB:Swiss-Prot Function]

UniProt: Q9Y286