SIRPA anticorps (PE)

N° du produit ABIN7867433

Cet anticorps Lapin Monoclonal détecte spécifiquement SIRPA dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SIRPA anticorps (PE) (ABIN7867433)

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRPA est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DM8

Détail du produit anti-SIRPA anticorps (PE)

Fonction: PE-conjugated Anti-SIRPa(DM8) antibody, Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: SIRPa

Sujet:

Synonyms: BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2

Target Background: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]

UniProt: P78324