TSH anticorps

N° du produit ABIN7867444

Cet anticorps anti-TSH Monoclonal Lapin (Clone EP254) (ABIN7867444) détecte spécifiquement TSH dans IHC (fp). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TSH anticorps (ABIN7867444)

Antigène: TSH (Thyroid Stimulating Hormone (TSH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TSH est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: EP254

Détail du produit anti-TSH anticorps

Fonction: Anti-TSH Rabbit Monoclonal Primary Antibody (Clone: EP254)

Isotype: IgG

Information d'application

Indications d'application:   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500  

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Solution in Tris Buffer, pH 7.3-7.7, with 1 % BSA and

Stock: 4 °C

Stockage commentaire: Tightly closed. Recommended storage temperature 2 - 8 °C

Détails sur TSH

Antigène: TSH (Thyroid Stimulating Hormone (TSH))

Autre désignation: TSH

Sujet: Optional[Synonyms]: Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit, which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones: Follicle stimulating hormone and luteinizing hormone and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors and the differential identification of primary and metastatic tumors in the pituitary gland.