Recombinant p63 anticorps (AA 1-100)

N° du produit ABIN7867896

L’anticorps anti-p63 Monoclonal Lapin est utilisé pour la détection de p63 dans des échantillons de Humain. Il a été validé pour ELISA, IHC (p) et FACS.

Aperçu rapide pour Recombinant p63 anticorps (AA 1-100) (ABIN7867896)

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp p63 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: P40-4396R

Détail du produit anti-p63 anticorps

Épitope: AA 1-100

Fonction: Recombinant deltaNp63 Antibody / p40

Purification: Protein A affinity

Immunogène: A portion of amino acids 1-100 was used as the immunogen for the recombinant deltaNp63 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant deltaNp63 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant deltaNp63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur p63

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Autre désignation: deltaNp63

Sujet: P40, the deltaN form of p63, is thought to function as a stem cell factor, responsible for maintaining cells in an uncommitted state with regenerative potential a role that may be recapitulated in tumors derived from these cells. p40 is normally expressed in the basal or progenitor cell layer of stratified epithelia (eg. squamous, urothelial, bronchial), basal cells of some glandular epithelia (eg. prostate), as well as myoepithelial cells of breast and salivary glands, trophoblasts and thymic epithelial cells. In tumor tissues, p40 expression is specific for squamous cell carcinoma. p40 is equivalent to p63 in sensitivity for lung squamous cell carcinoma, but it is markedly superior to p63 in specificity, which eliminates a potential pitfall of misinterpreting a p63-positive adenocarcinoma or unsuspected lymphoma as squamous cell carcinoma. p40 appears to be a more reliable marker for squamous cell carcinoma.

UniProt: Q9H3D4