Recombinant WT1 anticorps (AA 1-100)

N° du produit ABIN7867898

Cet anticorps Souris Monoclonal détecte spécifiquement WT1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant WT1 anticorps (AA 1-100) (ABIN7867898)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RWT1-6908

Détail du produit anti-WT1 anticorps

Épitope: AA 1-100

Fonction: Recombinant WT1 Antibody / Wilms Tumor 1

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1-100 was used as the immunogen for the recombinant WT1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant WT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant WT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1

Sujet: The WT1 gene located at chromosome 11p13 codes for a transcription factor, a DNA-binding nucleoprotein, that plays a role primarily in the development of genitourinary organs. There are at least eight isoforms ranging between 52 and 62 kDa produced by a combination of alternative splicing and RNA editing. WT1 is synthesized and reside in the cytoplasm in an inactive form. When activated through phosphorylation it is translocated to the nucleus. In tumor tissues, WT1 is detected in tumor cells of Wilms Tumor (also known as nephroblastoma) and mesothelioma. Additionally, WT1 expression has been found in ovarian serous carcinomas and some breast carcinomas. WT1 is particularly used for distinguishing malignant mesothelioma and ovarian serous carcinoma from non-serous carcinomas.

UniProt: P19544

Pathways: Tube Formation