Recombinant Gastrin anticorps (AA 1-101)

N° du produit ABIN7867908

L’anticorps anti-Gastrin Monoclonal Lapin est utilisé pour la détection de Gastrin dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Gastrin anticorps (AA 1-101) (ABIN7867908)

Antigène: Gastrin (GAST)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Gastrin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GAST-8646R

Détail du produit anti-Gastrin anticorps

Épitope: AA 1-101

Fonction: Recombinant Gastrin Antibody

Purification: Protein A affinity

Immunogène: A portion of amino acids 1-101 from human GAST protein was used as the immunogen for the recombinant Gastrin antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant Gastrin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant Gastrin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Gastrin

Antigène: Gastrin (GAST)

Autre désignation: Gastrin

Sujet: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

UniProt: P01350