OCT4 anticorps (AA 1-134)
Aperçu rapide pour OCT4 anticorps (AA 1-134) (ABIN7868118)
Antigène
Voir toutes OCT4 (POU5F1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 1-134
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Fonction
- Oct4 Antibody / POU5F1 (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- A portion of amino acids 1-134 was used as the immunogen for the Oct4. antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal dilution of the Oct4 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Aliquot the Oct4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Autre désignation
- Oct4
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Sujet
- Oct4 Transcription factor that binds to the octamer motif (5). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Interacts with UBE2I and ZSCAN10. Interacts with PKM2. Interacts with WWP2. Transcriptional activity is positively regulated by PKM2. Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. Belongs to the POU transcription factor family. Class- 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
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UniProt
- Q01860
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Pathways
- Stem Cell Maintenance
Antigène
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