Vinculin anticorps (AA 1-149)

N° du produit ABIN7868181

L’anticorps anti-Vinculin Polyclonal Lapin est utilisé pour la détection de Vinculin dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour Vinculin anticorps (AA 1-149) (ABIN7868181)

Antigène: Vinculin (VCL)

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vinculin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Vinculin anticorps

Épitope: AA 1-149

Fonction: Vinculin Antibody / VCL

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-E149) was used as the immunogen for the Vinculin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Vinculin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Vinculin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Vinculin

Antigène: Vinculin (VCL)

Autre désignation: Vinculin

Sujet: In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. It is mapped to 10q22.2. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2