CEBPG anticorps (AA 1-150)

N° du produit ABIN7868182

Cet anticorps anti-CEBPG Polyclonal Lapin (ABIN7868182) détecte spécifiquement CEBPG dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CEBPG anticorps (AA 1-150) (ABIN7868182)

Antigène: CEBPG (CCAAT/enhancer Binding Protein (C/EBP), gamma (CEBPG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEBPG est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-CEBPG anticorps

Épitope: AA 1-150

Fonction: CEBPG Antibody / CCAAT/enhancer-binding protein gamma

Purification: Immunogen affinity purified

Immunogène: E.coli-derived human CEBPG recombinant protein (Position: M1-Q150) was used as the immunogen for the CEBPG antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CEBPG antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CEBPG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CEBPG

Antigène: CEBPG (CCAAT/enhancer Binding Protein (C/EBP), gamma (CEBPG))

Autre désignation: CEBPG

Sujet: CEBPG antibody targets CCAAT/enhancer-binding protein gamma, a member of the CEBP family of transcription factors that regulate genes involved in immune response, metabolism, and cell differentiation. CEBPG lacks a canonical transactivation domain and instead acts as a dimerization partner for other CEBP family members such as CEBPA, CEBPB, and CEBPD, influencing transcription through heterodimer formation. This modulatory activity enables CEBPG to fine-tune expression of genes associated with inflammation, DNA repair, and oxidative stress responses. The protein is localized primarily in the nucleus, where it binds to CCAAT motifs within promoter regions and modulates transcriptional outcomes depending on its dimerization partner.

CEBPG is encoded by the CEBPG gene located on chromosome 19q13.11 and produces a protein of approximately 15 kilodaltons. It is ubiquitously expressed but particularly abundant in immune cells, liver, and lung tissues. Through interaction with CEBPB, CEBPG contributes to the regulation of cytokine expression, lipid metabolism, and acute phase responses. In addition to its transcriptional role, CEBPG has been linked to DNA damage tolerance pathways, where it may cooperate with ATF4 to activate antioxidant genes during cellular stress. The CEBPG antibody is therefore widely used in studies of transcriptional regulation, inflammation, and stress response signaling.

Research indicates that CEBPG participates in regulatory networks controlling macrophage activation and epithelial defense responses. Overexpression or silencing of CEBPG affects the expression of downstream effectors such as SOD2, GPX1, and TNF, linking this factor to redox balance and inflammatory signaling. Because of its cooperative interactions with other CEBP proteins, CEBPG serves as an important hub in transcriptional cascades influencing differentiation and immune adaptation. The CEBPG antibody is validated for western blotting, immunofluorescence, and chromatin immunoprecipitation assays, enabling analysis of protein expression and DNA-binding activity. NSJ Bioreagents provides this antibody for researchers studying gene regulation, stress adaptation, and cellular defense mechanisms.

UniProt: P53567

Pathways: Positive Regulation of Response to DNA Damage Stimulus