Cofilin 2 anticorps (AA 1-166)

N° du produit ABIN7868233

Cet anticorps anti-Cofilin 2 Monoclonal Souris (Clone CFL2-9963) (ABIN7868233) détecte spécifiquement Cofilin 2 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Cofilin 2 anticorps (AA 1-166) (ABIN7868233)

Antigène: Cofilin 2 (CFL2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cofilin 2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CFL2-9963

Détail du produit anti-Cofilin 2 anticorps

Épitope: AA 1-166

Fonction: Cofilin 2 Antibody / CFL2

Purification: Protein G affinity

Immunogène: A portion of amino acids 1-166 from human CFL2 protein was used as the immunogen for the Cofilin 2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cofilin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Cofilin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Cofilin 2

Antigène: Cofilin 2 (CFL2)

Autre désignation: Cofilin 2

Sujet: Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis