SNAIL anticorps (AA 1-170)
Aperçu rapide pour SNAIL anticorps (AA 1-170) (ABIN7868241)
Antigène
Voir toutes SNAIL (SNAI1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-170
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Fonction
- SNAI1 Antibody / SNAIL
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids M1-K170) was used as the immunogen for the SNAI1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the SNAI1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the SNAI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SNAIL (SNAI1)
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Autre désignation
- SNAI1
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Sujet
- The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.
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UniProt
- O95863
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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