Centrin 1 anticorps (AA 1-172)

N° du produit ABIN7868245

Cet anticorps anti-Centrin 1 Monoclonal Souris (Clone CETN1-9878) (ABIN7868245) détecte spécifiquement Centrin 1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Centrin 1 anticorps (AA 1-172) (ABIN7868245)

Antigène: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Centrin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CETN1-9878

Détail du produit anti-Centrin 1 anticorps

Épitope: AA 1-172

Fonction: CETN1 Antibody / Centrin 1

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1-172 from human CETN1 protein was used as the immunogen for the CETN1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CETN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CETN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Centrin 1

Antigène: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Autre désignation: CETN1

Sujet: EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

UniProt: Q12798