Centrin 1 anticorps (AA 1-172)

N° du produit ABIN7868246

Cet anticorps Souris Monoclonal détecte spécifiquement Centrin 1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Centrin 1 anticorps (AA 1-172) (ABIN7868246)

Antigène: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Centrin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CETN1-9877

Détail du produit anti-Centrin 1 anticorps

Épitope: AA 1-172

Fonction: CEN1 Antibody / Centrin 1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1-172 from human CETN1 protein was used as the immunogen for the CEN1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CEN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the CEN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Centrin 1

Antigène: Centrin 1 (CETN1) (Centrin, EF-Hand Protein, 1 (CETN1))

Autre désignation: CEN1

Sujet: EF-hand type Ca2+-binding proteins consists of several family members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle, and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles, and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.

UniProt: Q12798