ITPA anticorps (AA 1-194)
Aperçu rapide pour ITPA anticorps (AA 1-194) (ABIN7868347)
Antigène
Voir toutes ITPA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-194
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Fonction
- ITPA Antibody / Inosine triphosphate pyrophosphatase / ITPase
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived human recombinant protein (amino acids M1-A194) was used as the immunogen for the ITPA antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the ITPA antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the ITPA Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ITPA (Inosine Triphosphatase (ITPA))
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Autre désignation
- ITPA
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Sujet
- Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in yeast S. cerevisiae, the protein is also encoded by some RNA viruses of the Potyviridae family. This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
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UniProt
- Q9BY32
Antigène
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