HSPB8 anticorps (AA 1-196)

N° du produit ABIN7868355

L’anticorps anti-HSPB8 Monoclonal Souris est utilisé pour la détection de HSPB8 dans des échantillons de Humain et Rat. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour HSPB8 anticorps (AA 1-196) (ABIN7868355)

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSPB8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 7D8

Détail du produit anti-HSPB8 anticorps

Épitope: AA 1-196

Fonction: HSP22 Antibody / HSPB8

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-T196) was used as the immunogen for the Hsp22 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Hsp22 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Hsp22 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HSPB8

Antigène: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Autre désignation: HSP22

Sujet: Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

UniProt: Q9UJY1