G-CSF anticorps (AA 1-200)

N° du produit ABIN7868453

Cet anticorps Souris Monoclonal détecte spécifiquement G-CSF dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour G-CSF anticorps (AA 1-200) (ABIN7868453)

Antigène: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp G-CSF est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CSF3-4599

Détail du produit anti-G-CSF anticorps

Épitope: AA 1-200

Fonction: GCSF Antibody / CSF3

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the GCSF antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the GCSF antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the GCSF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur G-CSF

Antigène: G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))

Autre désignation: GCSF

Sujet: This mAb recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF s, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF s share 73 % sequence identity at the amino acid level.

UniProt: P09919

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization