IL18R1 anticorps (AA 1-200)

N° du produit ABIN7868579

Cet anticorps Souris Monoclonal détecte spécifiquement IL18R1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IL18R1 anticorps (AA 1-200) (ABIN7868579)

Antigène: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL18R1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL18R1-7593

Détail du produit anti-IL18R1 anticorps

Épitope: AA 1-200

Fonction: IL-18R alpha Antibody / IL18R1

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL-18R alpha antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the IL-18R alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IL-18R alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IL18R1

Antigène: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Autre désignation: IL-18R alpha

Sujet: Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Gamma production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1Alpha or IL-1beta. The association of IL-18 to IL-18R leads to activation of NFkB. At present two subunits of IL-18R have been characterized: IL-18RAlpha and IL-18Rbeta. IL-18RAlpha has been described as the ligand-binding chain and IL-18Rbeta as the signal-transduction chain.

UniProt: Q13478