Cet anticorps anti-Keratin 72 Monoclonal Lapin (Clone KRT6-8267R) (ABIN7868626) détecte spécifiquement Keratin 72 dans IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
KRT72
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
Optimal dilution of the KRT6 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Aliquot the KRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
Keratin 72 (KRT72)
Autre désignation
KRT6
Sujet
Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.