Recombinant Keratin 72 anticorps (AA 1-200)

N° du produit ABIN7868627

Cet anticorps Lapin Monoclonal détecte spécifiquement Keratin 72 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Keratin 72 anticorps (AA 1-200) (ABIN7868627)

Antigène: Keratin 72 (KRT72)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 72 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT6-8267R

Détail du produit anti-Keratin 72 anticorps

Épitope: AA 1-200

Fonction: KRT6 Antibody / Cytokeratin 6

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein (within amino acids 1-200) from the human protein was used as the immunogen for the KRT6 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the KRT6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the KRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Keratin 72

Antigène: Keratin 72 (KRT72)

Autre désignation: KRT6

Sujet: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

UniProt: P02538