Recombinant LAMP3 anticorps (AA 1-200)

N° du produit ABIN7868637

L’anticorps anti-LAMP3 Monoclonal Souris est utilisé pour la détection de LAMP3 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant LAMP3 anticorps (AA 1-200) (ABIN7868637)

Antigène: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAMP3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RLAMP3-9131

Détail du produit anti-LAMP3 anticorps

Épitope: AA 1-200

Fonction: Recombinant LAMP-3 Antibody / CD63

Purification: Protein A/G affinity

Immunogène: A recombinant fragment (within amino acids 1-200) of human CD63 protein was used as the immunogen for the recombinant LAMP-3 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant LAMP-3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant LAMP-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur LAMP3

Antigène: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Autre désignation: LAMP-3

Sujet: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

UniProt: P08962