Recombinant MYH11 anticorps (AA 1-200)

N° du produit ABIN7868671

Cet anticorps anti-MYH11 Monoclonal Lapin (Clone MYH11-7610R) (ABIN7868671) détecte spécifiquement MYH11 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant MYH11 anticorps (AA 1-200) (ABIN7868671)

Antigène: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MYH11 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MYH11-7610R

Détail du produit anti-MYH11 anticorps

Épitope: AA 1-200

Fonction: SMMHC Antibody / MYH11

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the SMMHC antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the SMMHC antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SMMHC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MYH11

Antigène: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Autre désignation: SMMHC

Sujet: Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development. SM-MHC stains the intact myoepithelial cell (MEC) layers present in benign and in situ malignant breast and bronchioloalveolar lesions and is therefore very helpful in distinguishing between benign and malignant tumors. The antibody reacts with smooth muscle cells and myoepithelial cells, but not with myofibroblasts. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

UniProt: P35749