PON1 anticorps (AA 1-200)

N° du produit ABIN7868701

Cet anticorps anti-PON1 Monoclonal Souris (Clone PON1-1351) (ABIN7868701) détecte spécifiquement PON1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PON1 anticorps (AA 1-200) (ABIN7868701)

Antigène: PON1 (Paraoxonase 1 (PON1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PON1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PON1-1351

Détail du produit anti-PON1 anticorps

Épitope: AA 1-200

Fonction: Paraoxonase 1 Antibody / PON1

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Paraoxonase 1 antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the Paraoxonase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Paraoxonase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PON1

Antigène: PON1 (Paraoxonase 1 (PON1))

Autre désignation: Paraoxonase 1

Sujet: Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

UniProt: P27169