T-Bet anticorps (AA 1-200)

N° du produit ABIN7868764

Cet anticorps anti-T-Bet Monoclonal Souris (Clone TBX21-6724) (ABIN7868764) détecte spécifiquement T-Bet dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour T-Bet anticorps (AA 1-200) (ABIN7868764)

Antigène: T-Bet

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp T-Bet est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: TBX21-6724

Détail du produit anti-T-Bet anticorps

Épitope: AA 1-200

Fonction: TBX21 Antibody / T-bet (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the TBX21 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the TBX21 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the TBX21 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur T-Bet

Antigène: T-Bet

Autre désignation: TBX21

Sujet: T helper (Th) lymphocytes differentiate into two unique subsets, Th1 and Th2, which differ both in function and in the cytokines they secrete. Th1 and Th2 cytokines promote the growth and differentiation of their subset, and inhibit the growth and differentiation of the opposing subset. T-bet (T-box expressed in T cells) is a Th1-specific T-box transcription factor that controls the expression of the Th1 cytokine, IFN-g. T-bet also converts effector Th2 cells into the opposing Th1 subset. T-bet is selectively expressed in Th1 cells. The level of T-bet expression is increased by signals mediated by the T cell receptor (TCR). IL-12 also induces an increase in the level of T-bet. T-bet was originally isolated from nuclear extracts of resting and PMA/ionomycin-activated AE7 cells. It is expressed in low levels in AE7 cells, and in increased levels in stimulated AE7.

UniProt: Q9UL17