Recombinant p63 anticorps (AA 1-200)

N° du produit ABIN7868784

L’anticorps anti-p63 Monoclonal Souris est utilisé pour la détection de p63 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant p63 anticorps (AA 1-200) (ABIN7868784)

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p63 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RTP63-6941

Détail du produit anti-p63 anticorps

Épitope: AA 1-200

Fonction: Recombinant TP63 Antibody / Tumor protein 63 (azide and preservative free)

Purification: Protein A affinity

Immunogène: A portion of amino acids 1-200 was used as the immunogen for the recombinant TP63 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant TP63 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant TP63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur p63

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Autre désignation: TP63

Sujet: P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

UniProt: Q9H3D4