PCMT1 anticorps (AA 1-227)

N° du produit ABIN7868871

L’anticorps anti-PCMT1 Polyclonal Lapin est utilisé pour la détection de PCMT1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour PCMT1 anticorps (AA 1-227) (ABIN7868871)

Antigène: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCMT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-PCMT1 anticorps

Épitope: AA 1-227

Fonction: PCMT1 Antibody / Protein-L-isoaspartate(D-aspartate) O-methyltransferase

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids M1-K227) was used as the immunogen for the PCMT1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PCMT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PCMT1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PCMT1

Antigène: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Autre désignation: PCMT1

Sujet: Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization