ANAPC5 anticorps (AA 1-266)

N° du produit ABIN7869004

Cet anticorps anti-ANAPC5 Polyclonal Lapin (ABIN7869004) détecte spécifiquement ANAPC5 dans WB, ELISA, FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ANAPC5 anticorps (AA 1-266) (ABIN7869004)

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC5 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-ANAPC5 anticorps

Épitope: AA 1-266

Fonction: Apc5 Antibody / Anaphase-promoting complex subunit 5

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids M1-D266) was used as the immunogen for the Apc5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Apc5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Apc5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ANAPC5

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Autre désignation: Apc5

Sujet: Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

UniProt: Q9UJX4

Pathways: M Phase