KCNIP2 anticorps (AA 1-270)

N° du produit ABIN7869016

Cet anticorps anti-KCNIP2 Monoclonal Souris (Clone KCNIP2-7588) (ABIN7869016) détecte spécifiquement KCNIP2 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour KCNIP2 anticorps (AA 1-270) (ABIN7869016)

Antigène: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KCNIP2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KCNIP2-7588

Détail du produit anti-KCNIP2 anticorps

Épitope: AA 1-270

Fonction: KCNIP2 Antibody / KChIP2

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein (within amino acids 1-270) from the human protein was used as the immunogen for the KCNIP2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the KCNIP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the KCNIP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur KCNIP2

Antigène: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Autre désignation: KCNIP2

Sujet: In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4Alpha-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain, KChIP2 (KCNIP2) expressed in heart, brain, and lung, and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain, KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99 % nucleotide homology to DREAM, suggesting that KChIPs may have activity beyond modulation of Kv4 channels.

UniProt: Q9NS61