HAX1 anticorps (AA 1-279)

N° du produit ABIN7869041

Cet anticorps Lapin Polyclonal détecte spécifiquement HAX1 dans WB, ELISA, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HAX1 anticorps (AA 1-279) (ABIN7869041)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-HAX1 anticorps

Épitope: AA 1-279

Fonction: HAX1 Antibody / HCLS1-associated protein X-1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M1-R279) was used as the immunogen for the HAX1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HAX1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HAX1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1

Sujet: HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization